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KMID : 0371319930450060920
Journal of the Korean Surgical Society
1993 Volume.45 No. 6 p.920 ~ p.928
A Clinical Study on Surgical Thyroid Nodules


Abstract
The thyroid nodules are the most common endocrine disease requiring surgical management. Up to date, various diagnostic techniques and surgical management have been developed. Authors analysed 2285 cases of thyroid2285 cases of thyroid nodules
who
were
treated at Department of Surgery, Pusan National University for the duration of 10 years fro January 1980 to December 1989 and the results obtained were summerized as follows:
1) Patients were composed of 1729 cases(75.8%) of benign nodule and 558 cases924.5%) of malignant nodule. Benign nodule was prevalent in third and fort decade comparing with malignant nodule was fifth and fort decade. The sexual distribution
revealed
female preponderance with 1 : 10.8 in benign nodule and 1 : 93 in malignant nodule.
2) The histopathologic classification of benign nodule in decreasing order of frequency were follicular adenoma 1009 cases(54.8%), adenomatous goiter 573 cases(33.3%), simple cyst 65 cases (3.8%), and Hashimoto's thyroiditis 52 cases(3.0%). The
malignant disease were papillary adenocarcinoma 460 cases(82.4%), follicular adenocarcinoma 69 cases(12.4%), undifferentiated carcinoma 13 cases(2.0%), and medullary carcinoma 7 cases(1.0%).
3) Fine needle aspiration cytology was performed in 1758 cases and it showed 80.5% of sensitivity, 96.5% of specificity, 19.5% of false negative and 80% of accuracy.
4) The location of nodule was 87.8% in unilateral, 12.2% I bilateral.
5) On the radioiodine scanning, the incidence of benign nodule with cold nodule was 83.9% and the incidence of benign nodule with hot nodule was 7.5%. The incidence of thyroid carcinoma with cold nodule was 88.3% and the incidence of thyroid
carcinoma
with hot nodule was 4.6%.
6) Most cases of benign nodules were treated with lobectomy 82.3%, subtotal thyroidectomy 10.1% and subtotal lobectomy 3.0%. malignant nodules were treated with lobectomy with isthmusectomy 9.2%, total thyroidectomy 17.7%, subtotal thyroidectomy
15.4%
and any thyroidectomy with neck dissection 13.5%.
7) Postoperative complications were developed in 3.8% of benign nodules and 13.8% of malignant nodules.
KEYWORD
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